Can Humans Take Ivermectin, this article will give you a true reflection of the two drugs to reduce mortality rate,
The novel coronavirus, severe acute respiratory syndrome coronavirus SARS-CoV-2,
was first identified in December 2019, because of the explanation given for respiratory disease,
it is now designated coronavirus 2019, or Covid-19.1
Several medicinal agents are appraised for the treatment of Covid-19, but no antiviral agents have yet been shown to be efficacious.
WHAT IS REMDESIVIR (RDV)?
Remdesivir (RDV) is a type of broad-spectrum(effective against a wide range of organisms like insects or bacteria a broad-spectrum antibiotic), an antiviral medication called a nucleotide analog.
COVID-19 is an RNA virus. (RNA is the molecular transcription tool organisms use to build proteins using DNA instructions.)
RNA viruses are dependent on an RNA polymerase enzyme to grow the RNA chain. Remdesivir substitutes this RNA polymerase enzyme,
meaning the RNA can’t develop so the virus cannot replicate itself.
What does Remdesivir cost?
Remdesivir (Veklury) was the first medical product approved for the treatment of SARS disease. It is indicated for the treatment of COVID19 Disease of hospitalized adults and children aged 12 years and older. It carries a weight of at least 40kg. Antivirals broad-spectrum is a nucleotide Analog Prodrug.
From October 1, 2020, Remdesevir remdesvir can be purchased from a German distributor amerisource.de. Overall the acquisition price for all five-day treatments is approximately $520 each. For a 100 ml vial.
Remdesivir was the first drug to be approved by the FDA to treat people with the dreaded disease covid-19 which have killed over 2.79M people worldwide so far and still climbing
Since the publication of the preliminary report, dexamethasone has been shown to decrease mortality (25.7% within the usual care group vs. 22.9% within the dexamethasone group; P<0.001),
Since the publication of the preliminary report, dexamethasone has been shown to decrease mortality.
The use of the antiviral drug Remdesivir was the first of all drugs approved by the FDA for treating the dreaded SARS-CoV-2 virus.
Why is Ivermectin a potential COVID treatment?
The anemic drug was suspected to be a potential treatment for covid-19 but there is still not enough evidence to recommend its use despite widespread support.
After such action, the support for ivermectin has circulated both online and in WhatsApp, but many rumors have claimed the drug is being stopped because of it.
Some claim it is new hydroxychloroquine that treated COVI-19 with a considerable amount of online support but was found mainly ineffective. Tell me the rationale behind blocking the drug?
How long does Remdesivir take to work?
It is an effective treatment of COVID-19 disease in hospitalized adults and children aged 12 years and older who weigh at least 40 kg.
Although a variety of therapeutic agents are evaluated for the treatment of coronavirus disease 2019 (Covid-19), no antiviral agents are yet to point out any efficacious.
A series of randomized, double-blind, placebo-controlled trials of intravenous Remdesivir in adults who were hospitalized with Covid-19 and had evidence of lower tract infection.
Patients were randomly selected to receive either Remdesivir (200 mg loading dose on day 1, followed by 100 mg daily for up to 9 additional days) or a placebo for up to 10 days.
the first outcome was the recovery time, defined by either discharge from the hospital or hospitalization for infection-control purposes only.
What is Remdesivir and how does it work
Remdesivir works by interrupting the assembly of the virus. Coronaviruses have genomes made from RNA,
RNA- Ribonucleic Acid is a molecule similar to DNA, unlike DNA, RNA is single-stranded and as backbone made of alternating sugar and phosphate groups
Remdesivir interferes with one of the key enzymes the virus must replicate RNA. This prevents the virus from multiplying.
What are Remdesivir side effects?
Remdesivir may cause gastrointestinal symptoms (e.g., nausea), elevated transaminase levels, an increase in prothrombin time, and hypersensitivity reactions.
In the case of a serious allergic reaction, symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Liver function tests and prothrombin time should be obtained for all patients before Remdesivir is administered to them and during treatment as clinically indicated.
An infusion reaction may occur with Remdesivir with symptoms such as low blood pressure, nausea, vomiting, sweating, and shivering. Your healthcare professionals should monitor for side effects during Remdesivir treatment.
This investigational product may contain inactive ingredients, which can cause allergic reactions or other problems.
Limited information is known about this drug, at this time about other medical conditions that may affect how Remdesivir works or how Remdesivir may affect other medical conditions.
Some medical conditions that must be taken into consideration during Remdesivir treatment include kidney disease, liver disease.
Information is limited and it is unknown at this time how safe and effective Remdesivir is for older adults, children, or pregnant women, or if it affects nursing infants.
More trials are needed to determine how safe and effective are Remdesivir for older adults and children.
The antiviral drug Remdesivir has proven to shorten the recovery time for patients hospitalized with COVID-19, which was based on results from the completed trial held recently.
Remdesivir improved mortality rates for those patients receiving supplemental oxygen (4% with Remdesivir versus 13% with placebo at day 29 of treatment).
All-cause fatality among all patients was 11% with Remdesivir and 15% with placebo at day 29, but this difference between the treatment groups was not large enough to rule out chance.
The preliminary findings hadn’t shown an effect on fatality.
Data shows that Remdesivir was superior to the placebo in shortening recovery time in adults who were hospitalized with covid-19 and had evidence of lower respiratory tract infection.
What Is Ivermectin For Humans?
Now let’s dive into the fact that Ivermectin may or may not reduce mortality rate or cure covid-19, now let the facts speak for themselves.
Ivermectin was first discovered within the late-1970s at the Kitasato Institute. japan.
it was first used to treat Onchocerciasis(or River Blindness) in humans in 1988.
The flagship drug ivermectin, an extract of avermectin—originating solely from one microorganism isolated from Japanese soil.
It was first introduced as a veterinary drug, its sole purpose is to kill a wide range of internal and external parasites
It has also been used to successfully overcome several other human diseases and new uses for it are continually being found
What is Remdesivir for
Ivermectin tablets is an FDA-approved anti-parasitic drug, that in recent years, along with other groups,
have shown to have anti-viral activity against a wide range of viruses in an artificial environment
Ivermectin tablets were approved to be used in humans for the
therefore the ivermectin topical formulations are approved for human use by prescription just for the treatment of external parasites like headlice, river blindness(onchocerciasis),
helminthiases, scabies, and yellow fever more clinical trials are needed before they can be approved for widespread use.
It is also proven to be effective against other viruses like
human immunodeficiency virus-1(HIV-1), simian virus, dengue virus,
Venezuelan equine encephalitis virus, which acts as an inhibitor a substance that reduces or suppresses the activity of another substance (such as an enzyme)
Ivermectin has continually proved to be astonishingly safe for human use. Indeed, it is such a safe drug, with minimal side effects
About 3.7 billion doses of ivermectin have been dispense worldwide
- nausea (2%)
- diarrhea (2%)
- peripheral edema (3%),
- tachycardia (3%)
- dizziness (3%)
- headache (6%),
- dysmenorrhea (5.5%),
- upper respiratory infection symptoms (1.8%),
NOTE: The big companies are telling you that the drug ivermectin is not good for you and is of danger to your health and wellbeing and that it should not be used to fight covid-19, because of the numerous side effects, when the truth is all synthetic drugs have serious side effects which are a danger to you, so the choice is yours wheater or not you want to use ivermectin or not, to save your life.
A group of individual that took part in the clinical trials has evaluated the use of ivermectin for the prevention and treatment of COVID-19
Confirmed hospitalize patients with the COVID-19 between March 15 and May 11, 2020, treated with or without ivermectin were reviewed. Two hundred eighty patients,
173 treated with ivermectin and 107 without ivermectin were selected at random.
Most of the patients in both groups also received doses of hydroxychloroquine, azithromycin, or both.
Univariate analysis showed lower mortality in the ivermectin group- 15.0% vs 25.2%,
Mortality also was lower among ivermectin-treated patients with severe pulmonary involvement – 38.8% vs 80.7%
One hundred ninety-six patients have included those whose, susceptibility-matched group.
The mortality rate was significantly lower in the ivermectin group 13.3% vs 24.5%
Prior to ivermectin, tell your doctor or pharmacist if you are allergic to it; or if you’ve got other allergies.
This product may contain inactive ingredients, which may cause allergic reactions or other problems. ask your pharmacist for more details.
Prior to using this medication, be sure to have a talk with your doctor or pharmacist about your medical record, especially of: liver problems. If you’ve got traveled or lived in the West or the Central African
Republic, you can be infected with certain parasites (such as Loa loa, African trypanosomiasis) that would cause problems with ivermectin treatment
Ivermectin Is Effective For COVID-19
- 100% of the 45 studies to date report positive effects. Random-effects meta-analysis for early treatment and pooled effects shows an 82% reduction, RR 0.18 [0.12-0.27], and prophylactic use shows 89% improvement, RR 0.11 [0.05-0.23]. Mortality results show a 75% lower mortality rate,
- 100% of the 24 Randomized Controlled Trials (RCTs) report positive effects, with an estimated 70% improvement,
- The probability that an ineffective treatment generated results as positive as the 45 studies to date is estimated to be 1 in 35 trillion (p = 0.000000000000028).
It is said that one of your first lines of defense is to choose a healthy lifestyle.
The following is a list of general good-healthy guidelines that is the only best step you can take toward naturally keeping your immune system working properly.
Every inch of your body, including your immune system, functions much better when protected from environmental assaults and bolstered by healthy-living strategies such as those listed below
- Don’t smoke, also avoid second-hand smoke
- Eat a healthy diet daily, high in fruits and vegetable content.
- Exercise regularly, at least 30 mins per day
- Maintain a healthy weight. the average for an adult’s weight is
- If you drink alcohol, drink only in moderation.
- Get adequate sleep, at least 8 hours will do the trick
- Take steps to avoid infection, such as washing your hands
frequently and cooking meats thoroughly and avoid rare meats
- Try to minimize stress.
Covid Self Care
- Call your health care provider or COVID-19 hotline to find out where and when to get a test.
- Cooperate with contact-tracing procedures to stop the spread of the virus.
- If testing is not available, stay home and away from others for 14 days.
- While you are in quarantine, do not go to work, to school or to public places. Ask someone to bring you supplies.
- Keep at least a 1-meter distance from others, even from your family members.
- Wear a medical mask to protect others, including if/when you need to seek medical care.
- Clean your hands frequently.
- Stay in a separate room from other family members, and if not possible, wear a medical mask.
- Keep the room well-ventilated.
- If you share a room, place beds at least 1 meter apart.
- Monitor yourself for any symptoms for 14 days.
- Call your health care provider immediately if you have any of these danger signs: difficulty breathing, loss of speech or mobility, confusion, or chest pain.
- Stay positive by keeping in touch with loved ones by phone or online, and by exercising at home.
The use of Ivermectin treatment in humans was associated with lower mortality during the treatment of COVID-19,
especially in patients with severe rheumatoid arthritis, especially in patients who required higher cause for oxygen or ventilatory support.
More randomized controlled trials would be needed to verify these findings.
Please consult your doctor if you decide to try this and other medications